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Lazio 4-1 Spal

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Mainz 2-1 Werder Bremen

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Manchester City 6-1 Southampton

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Chelsea 3-1 Crystal Palace

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Chievo 0-2 Sassuolo

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Parma 0-0 Frosinone

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Sampdoria 1-4 Torino

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Eibar 2-1 Alaves

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Rayo Vallecano 2-3 Barcelona

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Reims 1-0 Monaco

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Valencia 0-1 Girona

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Juventus 3-1 Cagliari

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Wolverhampton 2-3 Tottenham

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Bayer Leverkusen 1-4 Hoffenheim

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Fiorentina 1-1 Roma

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Lyon 1-1 Bordeaux

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Hertha Berlin 0-3 RasenBallsport Leipzig

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Arsenal 1-1 Liverpool

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Bayern Munich 1-1 Freiburg

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Schalke 3-1 Hannover

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Augsburg 2-2 Nurnberg

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Wolfsburg 0-1 Borussia Dortmund

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West Ham 4-2 Burnley

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Everton 3-1 Brighton

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Cardiff 0-1 Leicester

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Newcastle 1-0 Watford

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Real Madrid 2-0 Valladolid

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Inter Milan 5-0 Genoa

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Bournemouth 1-2 Manchester United

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Leganes 1-1 Atletico Madrid